zhè / me / zhòng / yào / de / xiàng / mù / chū / le / zhè / me / dà / de / wèn / tí / zhēn / jiào / rén / qíng / hé / yǐ / kān

这么重要的项目出了这么大的问题，真叫人情何以堪。

How can anyone bear it when such a serious problem occurs in such an important project?